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A six-year-old Caucasian boy was seen by a maxillofacial surgeon to be evaluated for surgical repair of severe jaw misalignment. The boy was deemed an appropriate candidate for surgery at this time, with a second surgery planned during his teen years to complete the correction. The boy was adopted, and no family history was available. He had no personal history of excessive bleeding or bruising. The pre-surgical CBC results including platelet count were within reference ranges. Pre-surgical hemostasis testing is as follows: Ryan L. Reference RangePT 10.5 9-12 secondsAPTT 40 32-46 secondsBleeding time 7 1-9 minutesRequired:Describe the principle and reagents for the PT and APTT.

User Spangen
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Answer: The PT and APTT are valuable blood clotting time determination principles.

Step-by-step explanation:

The principle of PT or prothrombin test determines the time required for the clot formation when additional calcium factor is added.

The principle of APTT or activated partial thromboplastin time is a test which determines the time required for the formation of the blood clot after the adding the calcium and phospholipid factors. This process activates the different blood clotting factors in the blood responsible for clotting of blood.

User Tim Elhajj
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