Question

You conduct a voltage clamp experiment in which you hold the presynaptic terminal of a glutamatergic neuron (a neuron that releases glutamate) at 0 mV. When you treat the terminal with TTX, an inward current is recorded. Which ion and ion channels are responsible for the current you observe? Group of answer choices Calcium; ligand-gated non-specific cation channels Sodium; ligand-gated non-specific cation channels Calcium; voltage-gated calcium channels Sodium; voltage-gated sodium channels Potassium; voltage-gated potassium channels

Answer 1

Calcium; voltage-gated calcium channels

Step-by-step explanation:

Voltage-dependent calcium channels represent a group of voltage-gated ion channels and they are recognized to be primary mediators of calcium entry induced by depolarization. These channels are localized in the membrane of excitable cells such as, for example, neuron cells. The potential difference across the membrane of neuron cells without physiological activity is named resting membrane potential. When there is no action potential, voltage-dependent calcium channels are normally closed.