Answer:
Average rate of change =250
Explanation:
Formula to determine average rate of change of the function,
Average rate of change =

Where
and
are the points representing number of years after year 2000.
Since
= 5 and
,

And

Now average rate of change =

=

= 250
Therefore, average rate of change of the number of influenza cases from 2005 to 2019 is 250.