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What made it possible for the Mississippi River Valley to support large cities?

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The big river was helpful to many people and other in the city it’s was basically a big source of water near by
User Bheussler
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Answer: Moving their goods down river to the Mississippi, to New Orleans, and then by sea to the cities on the Eastern Seaboard was cheaper and actually easier which made it a popular location for trade and to build cities . Also The Mississippi River provided water source to the people whom lived in the area.

Hope it helps <3 (Please tell me if you need anymore help)

User Jonathan Topf
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