48
1st seat 6 possible for each 6 only 1 possible(spouse) for seat 2
3rd seat 4 possible for each 4 only 1 possible(spouse) for seat 4
5th seat 2 possible for each 2 only 1 possible(spouse) for seat 6
6 x 4 x 2 = 48
OR 3 couples possible arrangements 3 x 2 x1 = 6
each couple 2 possible 2 x 2 x 2 = 8
therefore 6 x 8 = 48