Final answer:
The Roanoke Colony disappeared by 1590, and the only clue was the word 'Croatoan' left behind. The fate of the settlers remains unknown, supporting the true statement that they vanished and were never seen again.
Step-by-step explanation:
The mystery of the Roanoke Colony, often referred to as "the lost colony," remains unsolved to this day. In 1590, Governor John White returned to Roanoke Island to find the settlement deserted, with no trace of the 117 settlers except for the word "Croatoan" carved into a fence post. Theories suggest that the colonists may have moved to Croatoan Island, now known as Hatteras, and possibly integrated with the Native American population there.