Lipid accumulation product (LAP) is an index, which combines waist circumference (WC) and triglyceride (TG) reflecting lipid accumulation. Lipids are available to the body from three sources. They can be ingested in the diet, stored in the adipose tissue of the body, or synthesized in the liver. Lipid storage (especially sphingolipid and unesterified cholesterol) is found in liver and spleen. In the brain, glycolipid storage predominates, often with some decrease in myelin white matter. The condition is inherited as an autosomal recessive trait.
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