Simple question
slope of on le diagonal,whose coordinates are given=

now we know that diagonals of square are perpendicular to each other
and we also know that if there are two perpendicular lines have slope m1 and m2 respectively,then

so if one diagonal's slope is -1/4 then other diagonal's slope will be 4
now we know that all the equation of a line is in the form
y=mx+c
where m is slope
so simply put the value of m=4
y=4x+c...i)
we also know that the line of equationi) will pass through the midpoint coordinates of first diagonal
mid point of first diagonal ={(2-6)/2 ,(5+3)/2}=(-2,4)
put this value of x and y in i) equation
4=-8+c
c=12
hence putting the value of c in equation I) we get the equation of line as
y=4x+12
y-4x-12=0