Final answer:
Moving the capital to Constantinople shifted power and wealth away from Rome and contributed to the growth and prosperity of Constantinople. The influx of Christian refugees from Constantinople to cities like Venice and Florence played a role in sparking the Renaissance.
Step-by-step explanation:
Moving the capital to Constantinople had a significant effect on the city of Rome. First, Constantinople became the new center of power and wealth in the East, while Rome's prominence and importance diminished. Constantinople's strategic location as a hub of trade and travel between Europe and Asia contributed to its growth and prosperity. As a result, many Christian refugees fled Constantinople, eventually finding their way to cities like Venice and Florence, where they played a key role in sparking the Renaissance.