Answer:
Short answer: horribly.
Step-by-step explanation:
Natives were subjects of the Spanish crown, and to treat them as less than human “violated the laws of God, nature, and Spain.” Some Native Americans were forced to convert to Christianity; some were enslaved; some died of diseases from Europeans. The Spanish conquistadors were able to conquer Native American empires by spreading diseases to the Native Americans. Natives had no sort of protection from diseases therefor the Spanish received land while the Natives received death or enslavement.