Final answer:
RNA polymerase is not involved in DNA replication; it is involved in transcription. DNA replication is facilitated by enzymes such as helicase, DNA polymerase, and ligase.
Step-by-step explanation:
The enzyme that is not involved in DNA replication among the options provided is DNA polymerase, helicase, ligase, and RNA polymerase is D. RNA polymerase. During DNA replication, the enzymes involved include:
- Helicase, which unwinds the DNA double helix.
- DNA polymerase, which synthesizes the new DNA strands by adding nucleotides to a pre-existing strand.
- Ligase, joins the Okazaki fragments on the lagging strand to create a continuous DNA strand.
RNA polymerase, on the other hand, is involved in transcription, not DNA replication. It is responsible for synthesizing RNA from a DNA template.