Question

Good's buffers are compounds that are useful near neutral pH. MES buffer has pKa of 6.15, MOPS has pKa of 7.5, and HEPPS has pKa of 8.0.Required:Identify which Good's buffers are most effective near pH 7.0 and near pH 6.0.

Answer 1

MES for pH near to 6.0 and MOPS for pH near to 7.5.

Step-by-step explanation:

Hello,

In this case, given that the Henderson-Hasselbach equation is:

`pH=pKa+log(([Base])/([Acid]) )`

Good's buffers are those having pKa's near to the required pH since we look for a [Base]/[Acid] ratio to approach 1, thus, for a pH near to 7.0 a good buffer may be MOPS as it has a pKa of 7.5 and for a pH neat to 6.0 a good buffer may be MES as it has a pKa of 6.15.

Best regards.