Answer:
The majority of settles in North America experienced struggle when they arrived.
The majority of the first English settlers of the Roanoke and Jamestown colonies died, or disappeared in mysterious circumstances (in the case of the Roanoke colony).
Many other colonists came as indentured servants: they provided free labor in very harsh conditions to pay for their trip expenses. After a few years, they regained their freedom, but this did not mean that they would encounter prosperity afterwards.
African slaves struggled even more simply because they had no hope of becoming free. Besides, working conditions in the Southern plantations were very hard, as well as the treatment that they received.