The given question is incomplete as there is no figure attached. However, the correct figure is attached to the answer:
Answer:
Due to the amino acid substitutions, there will be alteration or modification in all the levels of protein structure, since there is an interchange n between two very crucial residues and two amino acids extremely different in nature.
Amino acid substitution is a change in one or more amino acids to another amino acid that takes place in the primary structure. This results in a change in secondary structure and then further. Thus the X should be placed on all the levels of protein structure.