Answer:
D) Two of her sons have hemophilia and one does not.
Step-by-step explanation:
The fact that Waldemar (her son) was hemophilic, is the best evidence to prove that Irene was heterozygous for hemophilia. Walderman received the Y chromosome from his father and an X chromosome from his mother. The X chromosome that he received from his mother carried the recessive allele for the trait, and this is why he had hemophilia. This means that there is no best evidence for Irene´s genotype than her son´s genotype.
I hope it helps you!