Question

Assume that cellular uptake rates and drug delivery rates of compounds 1 and 2 are identical. If the proposed mechanism of sensitization by Compound 1 is correct, what cancer cell treatment protocol is most likely to produce the most apoptosis 20 h after treatment?A.

Answer 1

The correct option is B: Administration of Compound 1 followed by Compound 2 after 0.5 h

Step-by-step explanation:

Administering both compounds simultaneously (as suggested in option A) would mean that some cells might be exposed to and interact with compound 2 before being exposed to compound 1. It was observed by the researchers that if the chemotherapeutic agent (compound 2) is given a half hour after giving sensitization agent (compound 1) gives better results.