Answer:
New experimental methods
Technological inventions
Step-by-step explanation:
A scientific theory is usually not based on speculation. Scientific theories must have a solid empirical basis.
However, experimental methods are limited to the caliber of equipments available at the time in which a theory is formulated. With advancing years, more technological sophistication leads to the invention of new instruments and ultimately, the development of new experimental methods.
These innovations are likely to alter existing scientific theories as new evidences emerge, hence the answer.