Answer:
Option D.
Explanation:
We need to find the circumstances that would likely make factoring the best method for solving a quadratic equation.
A quadratic equation is prime if its factors can not possible. So, option A is incorrect.
In a quadratic equation leading coefficient can not be zero. So, option B is incorrect.
For large numbers (coefficient or constant), quadratic formula is best method. So, option C is incorrect.
The difference of 2 perfect squares is:
In this case factoring is the best method.
Therefore, the correct option is D.