111k views
1 vote
Which of the following is NOT a mechanism used to temporally regulate the activity of maturation-promoting factor (MPF)?

A. the presence of mitotic cyclin
B. specific dephosphorylation
C. glycosylation
D. specific phosphorylation

User Yoke
by
6.2k points

1 Answer

3 votes

Answer:

C. glycosylation

Step-by-step explanation:

The maturation-promoting factor (MPF) is a cell cycle checkpoint that stimulates the passage from G2 (prophase) to M phase (metaphase). MPF also determines that DNA replication during the S (synthesis) phase did not produce any mutations. MPF is inactivated by kinase phosphorylation and activated by specific phosphatases capable of dephosphorylating this protein. On the other hand, glycosylation is a posttranslational modification where a carbohydrate (i.e., a glycan) is added to a functional group of another molecule. Many proteins undergo glycosylation, thereby playing a critical role in regulating protein function.

User Jasenkoh
by
6.2k points