Answer: 4. Colchicine is a drug that prevents microtubule assembly, thereby disrupting microtubule-based functions.
Step-by-step explanation:
Endocytosis can be defined as trapping of a substance from outside of the cell. Exocytosis can be defined as the process of fusion of the vesicles with the plasma membrane and excreting their contents outside the cell.
Colchicine is a drug that blocks the polymerization of microtubules in the cytoskeleton. This further prevents the transportation of vesicles out of the cell and in the cell. Thus this will prevent the exocytosis and endocytosis of the transport vesicles and will affect cellular metabolism.