Final answer:
The guideline 'Never distribute a handout after the beginning of a presentation' is not a good practice as flexibility in distribution timing can be beneficial. Consistent visual style and accessibility considerations are crucial for effective handouts.
Step-by-step explanation:
Of the given options, B. Never distribute a handout after the beginning of a presentation is not a good guideline to follow regarding the use of handouts. While it is often ideal to distribute handouts at the beginning of a presentation, there may be strategic reasons to distribute them at different times, such as to maintain audience attention or to highlight a specific part of the presentation. It is crucial to keep a consistent visual style, provide time for the audience to engage with the handouts, and consider accessibility for all audience members. Moreover, while mixing serif and sans serif fonts can be done tastefully, it requires a good design sense to ensure readability and coherence in the document. The goal is to maintain a balance that enhances the readability while not distracting from the content of the handout.