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Which of the following is responsible for the conversion of covalently closed circular DNA to supercoiled DNA of the plasmid of: a) endonuclease b) DNA gynase c) topa isomerase d) exonuclease

User Xwl
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Answer:

DNA gyrase

Step-by-step explanation:

DNA gyrase is a bacterial enzyme that plays an important role in catalyzing the negative supercoiling of circular chromosomal DNA. This enzyme belongs to a class of enzymes called topoisomerases which play a major role in transitioning of DNA structure. DNA gyrase conversion of covalently closed circular DNA to supercoiled DNA is ATP-dependent.

The importance of DNA gyrase cannot be overemphasized, because for DNA synthesis to occur, the DNA must have a single-stranded template, hence, DNA gyrase play an important role in unwinding the double-stranded DNA for replication. It has the ability to introduce negative supercoils and relax positive supercoils prior to replication.

User Pradeepa
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