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A new vaccination is being used in a laboratory experiment to investigate whether it is effective. There are 275 subjects in the study. Is there sufficient evidence to determine if vaccination and disease status are related? Vaccination Status Diseased Not Diseased Total Vaccinated 53 17 70 Not Vaccinated 62 143 205 Total 115 160 275

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Answer:

Step-by-step explanation:

From the give information: A new vaccination is being used in a laboratory experiment to investigate whether it is effective. There are 275 subjects in the study. Is there sufficient evidence to determine if vaccination and disease status are related?

Vaccination Status Diseased Not Diseased Total

Vaccinated 53 17 70

Not Vaccinated 62 143 205

Total 115 160 275

In this study, we have two variables ( Vaccination and diseases status ) The null and the alternative hypothesis can be stated as follows:

Null hypothesis: The two variables ( Vaccination and diseases status ) are independent

Alternative hypothesis : The two variables ( Vaccination and diseases status ) are dependent

The Chi-square test statistics can be computed as:

The Expected Values for the table can be calculated by using the formula:


E_i=(row \ total * column \ total)/(grand \ total)

Vaccination Status Diseased Not Diseased Total

Vaccinated 29.273 40.727 70

Not Vaccinated 85.727 119.273 205

Total 115 160 275


Chi - Square \ X^2 = ((O_i-E_i)^2)/(E_i)

Vaccination Status Diseased Not Diseased Total

Vaccinated 19.232 13.823 33.055

Not Vaccinated 6.564 45.573 52.137

Total 25.796 59.396 85.192

Therefore;

the Chi-Square Test Statistics = 85.192

For this study; we two rows and two columns

Therefore, the degree of freedom = (rows-1) × (columns-1)

the degree of freedom = (2 - 1) × (2 - 1)

the degree of freedom = 1 × 1

the degree of freedom = 1

Using the level of significance of ∝ = 0.05 and degree of freedom = 1 for the chi-square test

The p-value for the test statistics = 0.00001

Decision rule: Since the P-value is lesser than the level of significance , therefore we reject the null hypothesis at the level of significance of 0.05

Conclusion:

We accept the alternative hypothesis and conclude that the two variables

(Vaccination and diseases status ) are dependent i.e the vaccination and disease status are related

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