Question

Construct the sequence of events leading from a dietary vitamin C deficiency to symptoms such as bruising and breakdown of supporting tissues.

1. tissue levels of ascorbic acid is low
2. enzyme prolyl hydroxylase is inactive
3. proline is not hydroxylated
4. the triple helix is inadequately stabilized .
5. collagen breaks down
6. defects in tissues that depend on collagen
7. tissues that depend on collagen are subject to breakdown and bruising

Answer 1

1. the levels of ascorbic acid in the tissues are low

2. the enzyme prolyl hydroxylase is inactive

3. proline is not hydroxylated

4. The triple helix is inadequately stabilized.

5. collagen breaks down

6. collagen-dependent tissue defects

7. Collagen-dependent tissues are subject to breakdown and bruising

Step-by-step explanation:

Vitamin C deficiency or vitamin C hypovitaminosis generates an oatology called scurvy, in this pathology there are tendon problems and fragility at the tissue and vascular level.

This is because of the low antiquity of vitamin c that is necessary for the correct synthesis of collagen, the collagen helices formed by the fibroblast are considered of poor quality and thus do not fulfill the function of support, containment and body in the tissues.

Vessels are highly contained by collagen and tissues as well, which is why hematomas appear due to vessel rupture and blood exacerbation in the extracapillary medium.