Question

If two people with sickle cell trait have children, what is thechance that a child will have normal RBCs in both high-and low-oxygen environments? What is the chance that a child will have sickle cell disease? Write the possible genotypes in the Punnettsquare.

Answer 1

See the answer below

Step-by-step explanation:

The chance that a child from two people with sickle cell trait will have normal RBCs remains the same irrespective of the amount of oxygen in the environment. From the cross:

AS x AS

AA AS AS SS

Hence, the chance of having a child with normal RBCs in both high and low-oxygen environments is 1/4 or 25%.

The chance that a child will have sickle cell disease is also 1/4 or 25%.

The possible genotypes in a Punnet's square can be seen in the attached image