Question

Certain natural compounds and drugs being tested as treatments for diabetes lower glucose transport in intestinal or kidney epithelial cells, and thereby lower blood sugar levels. Addition of one such drug to the apical medium yields transport similar to that in Treatment 5, whereas its addition to the basolateral medium yields transport similar to that in Treatment 4. What is the most likely target of this drug, and what is the effect on this target?

Answer 1

Lowering serious blood glucose concentration and avoiding glycemic spikes (target).

The consequences of this seriously that by maintaining glycemia and glycemic levels the patient does not undergo glycosidization of cellular components, the first line of immune defense is not affected, blood vessels are not affected, affected cardiac pathologies are avoided, no Coagulation, scarring, and collagen synthesis are impaired.

Step-by-step explanation:

The increase in blood glucose is called glycemic peak or high blood glucose, this is what happens in diabetic patients.

These drugs at the intestinal level, generate a decrease in the speed of glucose absorption, thus avoiding glycemic spikes or high blood glucose levels, therefore maintaining constant values ​​that are easier for the administration of insulin via parenteral or oral hypoglycemic drugs.

This similar effect is found in sweeteners such as stevia, that is why it is recommended in diabetics, the difficulty of these drugs or these chemicals is that since the absorption of glucose is more lethargic, the glucose remains more in the intestines and drags masses of water or allows aqueous diffusion processes into the lumen of the intestine, thus promoting the appearance of instestinal breakdowns such as diarrhea.

That is why you have to be vigilant with hydration in these specific cases.

Diabetics having high glucose generate: cardiac, immunological, scarring, vascular alterations, obesity risks.