Question

Although small hairpin RNAs are used in RNAi-mediated destruction of a target mRNA, in order for them to be effective, the double-stranded RNA must be cleaved by which of one of the following?

1. exonuclease
2. RNA polymerase
3. dicer
4. RISC

Answer 1

Option C. Dicer

Step-by-step explanation:

Dicer is a dsRNA endoribonuclease like bacterial Class III RNaseIII that is encoded by the DICER1 gene contains a N-terminal ATP-subordinate RNA helicase motif or domain.

Dicer cuts or cleaves precursor RNA molecules to make miRNA molecules. MicroRNAs regulates gene expression by hindering the procedure of protein creation. In the initial step of making a protein from a gene, another sort of RNA called RNA (mRNA) is made and goes about as the plan for protein production.