Question

You are studying a population of squirrels on the south rim of the Grand Canyon and find that 9 squirrels out of 100 observed had a unique, solid black color variation. In other mammals, the solid black color variation is caused by a recessive allele, and you assume that to be the case with these squirrels. If the population is in Hardy-Weinberg equilibrium, which of the following would be true?

A. q2 = 0.09
B. .q2 = 0.9
C. The frequency of the black color allele is 0.3, the frequency of the dominant allele is 0.7
D. The frequency of the heterozygous genotype is 4.2%
E. A and C
Which of the following is/are possible applications for use of the CRISPR-Cas9 system?
A. Disable dominant deleterious genes
B. Turn on and off specific genes by disabling Cas9 nuclease activity and attaching it to a transcriptional activator or repressor protein
C. Study gene function
D. all of the above
Genome wide association studies are important for behavioral disorders because
A. Candidate genes can be identified for further study
B. They provide an association between genetic loci and phenotypes
C. They provide a tool to help understand how genetic and environmental factors interact to cause psychiatric disorders
D. all of the above

Answer 1

Explanation:

Ans-1.)

q 2 = 9 /100 (A) q = 0.3 (p + q) 2 = 1 p + q = 1 p = 1- q = 1 - 0.3 p = 0.7 * The frequency of black color allele is 0.3 and dominant allele is 0.7 (C)

* (A) and (C)

Ans -2.) CRISPR -Cas 9 system has very wide application :

* can be used to disable the dominant deleterious genes .

* Turn on and off by disabling Cas9 nuclease activity and attaching to a transcriptional activator or repressor protein.

* widely used to study function

* All the above (answer)

Ans-3.) Genome wide association studies are important to study behavioral disorders because

* candidate genes identified for further studies.

* Provide an association between genetic loci and phenotypes.

* Provide a tool to help understand how genetic and environmental factors interact to pyschiatric disorders

* All of the above (answer)