Alcohol use disorder, the medical term for alcoholism and alcohol abuse, has been linked to some specific genes. Having a close relative, such as a parent or sibling, who struggles with alcohol use disorder increases the chances that a person will also struggle with the same addiction.
If a person is predisposed to metabolize alcohol in such a way that the pleasurable effects are more prominent than feeling nauseous, overheating, or experiencing mood swings, the person may be more likely to develop alcohol use disorder.
(Sources, AmericanAddictionCenters)