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What are some of the implications of Directed Evolution?

User Manuel Brnjic
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Answer:

Directed evolution is the laboratory process by which biological entities with desired traits are created through rounds of genetic diversification. It can also be created through library screening or selection and has become one of the most useful tools in basic biology. It's role includes improving the stabilities or biochemical functions of proteins by repeated rounds of mutation and selection.

More simply said, directed evolution is a mimic of the natural evolution cycle in a laboratory setting.

It has indirectly revealed that single amino acid mutations can enhance properties such as catalytic activity or stability and that adaptation can often occur through pathways consisting of beneficial mutations.

User Sterling Diaz
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Answer:

Adaptive laboratory evolution selects many genome-wide mutations that contribute to the fitness of actively growing cultures, whereas directed evolution typically targets a specific gene for mutagenesis and then screens the resulting variants for a phenotype of interest, often independent of fitness effects.

Step-by-step explanation:

User TheAgent
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