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Explain the production of monoclonal antibodies and give an example of how they are used.

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Answer:

Monoclonal antibodies (mAbs) are produced by introducing an antigen to a mouse and then fusing polyclonal B cells from the mouse's spleen to myeloma cells. The resulting hybridoma cells are cultured and continue to produce antibodies to the antigen.

Step-by-step explanation:

An example of a monoclonal antibody is blinatumomab (Blincyto, Amgen), used to treat certain cancer, types of acute lymphocytic leukemia.

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