Question

Suppose a female child is affected by hemophilia (xhxh). Determine the likelihood that her father was also affected

by hemophilia. In your answer, be sure to explain your reasoning​

Answer 1

Hemophilia is an X-linked recessive disorder. The father of a female child affected by hemophilia would be a carrier of the disorder and pass down the mutated gene to his daughter, who would be a carrier as well.

Step-by-step explanation:

Hemophilia is an X-linked recessive disorder, which means it is passed down through the X chromosome. In females, two copies of the mutated gene are generally required to manifest the disease. Since the father in this case would have hemophilia, he would have one normal X chromosome and one mutated X chromosome (XhY) and would pass down the mutated gene to his daughters. However, since the daughters would also receive a normal X chromosome from their mother (XhX), they would not be affected by the disease but would be carriers.