Oppositely charged particles attract one another, while like charges repel each other. Imagine that a chemical cause the amino acids in an active site on an enzyme to change from a positive to a negative charge. How would this change MOST LIKELY affect the way this enzyme interacts with its negatively charged substrate?
a) it would cause the substrate to be repelled by the active site
b) it would cause the substrate to bind more tightly with the active site
c) it would have no affect on the way the substrate and active site bind together
d) it would cause the active site to bind to twice the usual number of substrates