Question

In the genetic disease cystic fibrosis, ducts in several organs become blocked by an excessive production of thick mucus. Although most cystic fibrosis deaths are due to lung damage, the disease also clogs bile ducts in the liver and pancreatic ducts in the pancreas. How does the thick mucus alter gastrointestinal function?

Answer 1

The GIT mucus lining of the GIT serve as a physical barrier to the movement of digested food substances.

The mucus also help to prevent inflammation of the bowels; by reducing or suppressing immune response to inflammation.

In Cystic fibrosis, the blockage of the ducts by the mucus, prevents enzymes from reaching the digestive food substances,. The resulting undigested food substances leads to bloating, pain, cramps, gas, smelly belch, constipation, and smelly stools.

Step-by-step explanation: