Answer:
4.
Step-by-step explanation:
Synteny oe syntenic gene is defined as the physical co-localization of genetic loci on the same chromosome within a speciesand inidvidual.
In the beginning of the meiosis process, when genes are present in the same chromosomes but very far, they undergo indepedent assort due to homologous recombination and the random exchnage of matching fragment in homologous chromosomes takes place. During the crossing over there are very less chances that all types of gametes are produced accurate frequency.
Hence, the correct answer is 4.