Question

The gene\ codes for the membrane-associated protein A, responsible for signal transduction. A mutant allele of this gene, Am, encodes a malfunctioning A protein, which has the same size as the wild type and still associates with the plasma membrane like the wild type, but does not function in signaling. With respect to the expression of the A proteins, the wild-type allele is:________.

a. haplo insufficient.
b. codominant to the Xm allele.
c. recessive to the Xm allele.
d. dominant to the Xm allele.
e. incompletely dominant to the Xm allele.

Answer 1

The correct answer is option a. "haplo insufficient".

Step-by-step explanation:

A wild-type allele in comparison to a mutant allele of a gene that results in a malfunctioning protein is considered to be haplo insufficient. Haploinsufficiency is a model of dominant gene phenomena that occurs in diploid organisms when a heterozygous combination of the wild type allele and the mutant allele is insufficient to produce a wild type condition. This is the case for the Am malfunctioning protein, where a mutant allele of the gene results in a protein that does not perform its signal transduction properly.