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Somatic hypermutation of V genes ​

User Vscharf
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Somatic hypermutation is a process in which point mutations build up in the antibody V-regions of both the heavy and light chains.

This process occurs at rates that are about 106-fold higher than the background mutation rates observed in other genes.

It allows B cells to mutate the genes that they use to produce antibodies. This then ensures the B cells to produce antibodies that are better able to bind to bacteria, viruses and other infections.

User Nitin Pund
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