Question

Some G protein‑coupled receptors are sensitive to hormones such as angiotensin II and oxytocin and act through compounds such as phospholipase C and IP3 . Complete the flowchart showing the cleavage of a membrane lipid to form compounds that ultimately cause the phosphorylation of specific proteins. The abbreviations used are phosphatidylinositol 4,5‑bisphosphate, PIP2 ; protein kinase C, PKC ; diacylglycerol, DAG ; inositol 1,4,5‑triphosphate, IP3 ; and phospholipase C, PLC . Which of the compounds can be considered second messengers? DAG Ser PLC Ca2+ IP3 PKC PIP2

Answer 1

see explaination

Step-by-step explanation:

a. Please kindly check attachment for the detailed solution.

b.

The molecules that relay signals, which are received at receptors to the target sites is called second messengers. The three major classes of second messengers are cyclic nucleotides, IP3 & DAG, and calcium ions. Thus, the different second messengers in the body are cAMP, cGMP, IP3, DAG, and Ca2+.

Thus, in the given case the correct options among the following are 1, 4, and 7.