Answer:
It challenged the supremacy clause of the government by rejecting the enforcement of federal government's tariffs of 1832.
Step-by-step explanation:
The Nullification Crisis in the beginning of the 1830s was a conflict between the Jackson Administration and the state of South Carolina over the question of federal tariffs. South Carolina didn't not agree to enforce the federal tariff of 1832.
The doctrine of nullification was proposed by John c. Calhoun stating that a state could nullify, or reject, a federal law which it considers as unconstitutional. This doctrine was first proposed by Thomas Jefferson in 1799. In his argument he said the Union was a league of sovereign states that had the right to limit the federal government. The nullification challenged the supremacy clause of the Constitution.