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How can an individual with a recessive genetic disorder have parents who are not afflicted?

User Aseem
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Both parents must be carriers, which means they have the heterozygous gene (one uppercase letter & one lower case letter). They will still carry that mutated gene (because they have a lower case letter), and their offspring will have a 25% chance of getting a recessive disorder. The percentage is low but still possible.
User Fluffy
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