Answer:
Option B
Step-by-step explanation:
Urea, the main nitrogenous excretory product of mammals and a major organic component of urine is cleared from the blood by the kidney. Urea's concentration builds up in the renal medulla as they leave through the walls of the cortical collecting duct and go into the interstitial fluid in the region of the inner medulla, then some diffuses into the descending loop of Henle.