Suppose you have a table like this one:
Notice how the difference between the consecutive squares is a sequence of odd numbers:
4 - 9 = -5
1 - 4 = -3
0 - 1 = -1
1 - 0 = 1
4 - 1 = 3
9 - 4 = 5
Notice also how the differences between *these* differences is fixed. That is, the second-order differences are
-3 - (-5) = 2
-1 - (-3) = 2
1 - (-1) = 2
3 - 1 = 2
5 - 3 = 2
A sequence of fixed second-order differences indicates a function has quadratic behavior.
Here's another example, where the function is unknown. Consider the sequence,
22, 11, 4, 1, 2, 7, 16
The first-order differences are
-11, -7, -3, 1, 5, 9
and the second-order differences are
4, 4, 4, 4, 4
So this sequence is also quadratic.