Question

Which of the following is not true of homologous recombination? Only occurs between regions of DNA sharing >50 basepairs of nearly identical sequence. Can repair a collapsed replication fork. Always accompanied by some loss of DNA sequence. Responsible for crossing over at meiosis. Can repair a double-stranded break in chromosomal DNA.

Answer 1

Recombination

Step-by-step explanation:

Always accompanied by some loss of DNA sequence is not true of homologous recombination

• Homologous recombination is a type of genetic recombination which requires homology between two DNA molecules
• Single stranded break occurs in same position of both DNA, after that strand invasion occurs
• Each invading strand joins to the broken end of other DNA molecule, creating a Holliday junction
• Holliday junction predicts cross over or non cross over recombinant DNA, depends on whether cleavage is on vertical or horizontal plane
• Cleavage in vertical plane produces cross over recombinant consisting of two heteroduplex DNA