Question

Predict the effect of adding a non competitive inhibitor to the reaction mixture on the rate of reaction at a high substrate concentration. Support your prediction by describing how a non competitive inhibitor affects the structure and function of an enzyme.

Answer 1

A noncompetitive inhibitor can only bind to an enzyme with or without a substrate at several places at a particular point in time

Step-by-step explanation:

this is because It changes the conformation of an enzyme as well as its active site, which makes the substrate unable to bind to the enzyme effectively so that the efficiency of the enzyme decreases. A noncompetitive inhibitor binds to the enzyme away from the active site, altering/distorting the shape of the enzyme so that even if the substrate can bind, the active site functions less effectively and most of the time also the inhibitor is reversible