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Samples are used to make inferences about populations. Samples are easier to collect data from because they are practical, cost-effective, convenient and manageable. When are populations used in research? Populations are used when a research question requires data from every member of the population.
Sample size determination is the process of determining the appropriate number of subjects to include in a study. The appropriate sample size is defined as the minimum sample size required to achieve an acceptable chance of achieving a statistical criterion of interest (e.g. statistical significance, maximum interval width) for a proposed study. The methodology used to determine the appropriate sample size varies depending on the type of testing procedure used, the underlying assumptions etc. In addition, most sample size calculations will require pre-study estimates for the outcome of interest and additional nuisance parameters.
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