Question

1. The following statement is similar to those you might see on exams. Write a paragraph of 3-5 sentences describing 1) whether the statement is correct or incorrect and 2) the reasoning for your answer. Your answer should demonstrate your understanding of the physiological concepts underlying the statement and be written professionally. During strenuous exercise, the oxygen-hemoglobin dissociation curve shifts to the right. This rightward shift reflects an increase in the affinity of hemoglobin for oxygen and favors loading of O2 onto hemoglobin in the lungs. 2. The following statement is similar to those you might see on exams. Write a paragraph of 3-5 sentences describing 1) whether the statement is correct or incorrect and 2) the reasoning for your answer. Your answer should demonstrate your understanding of the physiological concepts underlying the statement and be written professionally. Compared to hemoglobin, myoglobin has a lower binding affinity for O2 and a higher O2 binding capacity, two characteristics that allow myoglobin to efficiently provide skeletal muscle cells with a readily-accessible reservoir of O2.

Answer 1

The oxygen dissociation curve represents the percentage saturation of Hb with oxygen at different partial pressure of oxygen. The different partial pressures gives sigmoid shapes to the curve. When this curves shifts to right, it indicates low affinity or binding of oxygen by the Hb. it also indicates the unloading or releases of Oxygen by Hb molecules at condition of low pressure. e,g in the muscles during strenuous exercise.However, when the curve shifts to the left, this indicate high affinity for oxygen, great binding, at high partial pressure of oxygen.e,g in the lungs to take oxygen and releases CO2.

Therefore in this scenario, the statement -. During strenuous exercise, the oxygen-hemoglobin dissociation curve shifts to the right. is correct. because oxygen is needed by the muscles therefore ,oxygen should be less binded by Hb, decrease affinity and easily unloaded to muscles.

The statement This rightward shift reflects an increase in the affinity of hemoglobin for oxygen and favors loading of O2 into hemoglobin in the lungs is wrong.

As explained above the rightwards shift indicated low affinity of Hb for oxygen(unloading)and favours unloading at the muscles because during strenuous exercise the partial pressure of oxygen is very low(but that of CO2 high) in the muscles which favours low oxygen molecules binding by Hb, and easy release to respiring cells.

Step-by-step explanation: