Question

A inhibitor of carbonic anhydrase would:______

a. decrease the amount of carbon dioxide dissolved in plasma.
b. increase the amount of bicarbonate formed in the blood.
c. increase blood pH.
d. interfere with oxygen binding to hemoglobin.
e. All of the answers are correct.

Answer 1

d. interfere with oxygen binding to hemoglobin

Step-by-step explanation:

Carbonic anhydrase inhibitors are commonly used as diuretic drugs (usually for treatment against high blood pressure), acting in the carbonic anhydrase enzime, in the proximal tubes of the kidneys.

To achieve this effect, these diuretics inhibit the reabsorption of sodium bicarbonate, and consequently, reducing its concentration in the blood due to the high excretion of this compound.

Thus, by eliminating more bicarbonate, an increase in the concentration of carbon dioxide in the blood plasma can occur, which makes it difficult to fix oxygen in the red blood cells, in addition to causing metabolic acidosis, by decreasing blood pH.

So the correct alternative is "D", while the others are false.

Answer 2

c. increase blood pH.

d. interfere with oxygen binding to hemoglobin.

Step-by-step explanation:

A inhibitor of carbonic anhydrase increases the pH of the blood due to prevent the production of carbonic acid from the carbon dioxide formed during cellular respiration. This carbonic acid decreases the pH of the blood so inhibitor of carbonic anhydrase is responsible for the increase in the pH. It also interfere with oxygen binding to hemoglobin because oxygen bind with hemoglobin in low pH but the pH is higher due to inhibitor of carbonic anhydrase.