Question

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.

Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

A. sER \to Golgi \to secretory vesicle \to environment
B. rER \to secretory vesicle \to Golgi \to environment
C. rER \to Golgi \to sER \to cytoplasm \to environment
D. cytoplasm \to rER \to Golgi \to secretory vesicle \to environment
E. rER \to Golgi \to secretory vesicle \to environment

Answer 1

E. rER \to Golgi \to secretory vesicle \to environment

Step-by-step explanation:

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead will follow the following sequence:

Rough endoplasmic reticulum (RER) (where the protien is being snthesized)-------------> Golgi apparatus (where the sorting and packaging of the protien occurs)-----------------------> Secretory vesicles-------------------------> Environment.

Hence E. rER \to Golgi \to secretory vesicle \to environment is the right answer.