Answer:
I'm not sure I understand the formatting. I don't know what the x is supposed to be for the middle term (-x(2.2x10^6)), so I dropped the x for the calculation. I also assumed all terms are to be added. If these assumptioons are correct, the answer is:
4.58012 x 10^8 or 4.6x10^8 (see below)
Explanation:
(4.8x10^8) - (2.2x10^6) + 1.2x10^4
(4.8x10^8) - (0.022x10^8) + (0.00012x10^8)
4.8
-0.22
+0.00012
4.58012
4.58012 x 10^8
There are only 2 significant digits (2.8x10^8) so if this is an answer relating to a scientific measurement, it would need to rounded to simply 4.6x10^8.