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Describe the mechanisms by which acetylcholine affects heart rate.
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Describe the mechanisms by which acetylcholine affects heart rate.
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Aug 17, 2023
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Describe the mechanisms by which acetylcholine affects heart rate.
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Acetylcholine slows the heart rate by activating the M2 muscarinic receptor (M2R) that, in turn, opens the acetylcholine-activated potassium channel (IK,ACh) to slow the firing of the sinus node.
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